Hydroxy propyl methyl cellulose (HPMC) Großhandel

Hydroxypropyl Methylcellulose (HPMC) Uses

Hydroxypropyl Methylcellulose (HPMC) is mainly derived from refined cotton/wood pulp, which is alkalized to obtain cellulose, and then added with propylene oxide and methyl chloride for etherification to obtain cellulose ether.

HPMC Cellulose act as thickener, water retaining agent, dispersant, stabilizer, emulsifier, binder, excipient, film former in various industries. HPM cellulose is widely used in construction dry-mixed mortar, pharmaceutical, petrochemical, ceramics, paper, synthetic resin, leather, food and cosmetics and other industries.

KimaCell® Hydroxypropyl Methylcellulose (HPMC) has the advantages of wide application, small unit usage, good modification effect, and environmental friendliness. HPMC products can significantly improve and optimize product performance in the field of its addition, which is conducive to improving resource utilization efficiency and product added value. Environmentally friendly additives that are essential in various fields.

1. HPMC In Pharmaceutical

In the field of medicine, Hydroxypropyl Methylcellulose (HPMC) is an important pharmaceutical excipient, which can be used in drug sustained and controlled release preparations, vegetable capsules, tablet coatings, suspending agents, tablet binders, tablet disintegrants and other application scenarios.

2. Hydroxypropyl Methyl Cellulose In Food

Food grade Hydroxypropyl Methylcellulose (HPMC) is a recognized safe food additive. It can be used as a food thickener, stabilizer and moisturizer to thicken, retain water, and improve taste. It is widely used in developed countries, mainly for baked food, collagen Protein casings, whipped cream, fruit juices, sauces, meat and other protein products, fried foods, etc. China, the United States, the European Union, and many other countries allow HPMC to be used as a food additive.

The proportion of food-grade Hydroxypropyl Methylcellulose (HPMC) used in food production in China is relatively low. The domestic market is still in the stage of application and promotion, coupled with the high price of food-grade HPMC, HPMC is used in fewer fields in food production in my country. However, with the improvement of income, the scale of the food industry is expected to maintain steady growth in the long run. Moreover, with the improvement of people's awareness of healthy food, the penetration rate of HPMC as a health additive will gradually increase. The consumption of HPMC in the food industry expected to grow further.

3. HPMC For Construction

In Construction drymix mortar industry, Hydroxypropyl Methylcellulose is used as a water-retaining agent and retarder for cement mortar to make the mortar pumpable. HPMC Used as a binder in plaster, plaster, putty powder or other building materials to improve spreadability and prolong work time. HPMC can be used as paste tile, marble, plastic decoration, paste reinforcement, and can also reduce the amount of cement. The water-retaining performance of HPMC prevents the slurry from cracking due to drying too quickly after application, and enhances the strength after hardening.

Hydroxypropyl Methylcellulose Benefits

Hydroxypropyl methylcellulose (HPMC) offers a wide range of benefits across different industries. HPMC versatile nature as thickener, stabilizer, film-former, and water-retaining agent makes it an indispensable ingredient in pharmaceuticals, food products, cosmetics, and construction materials. Whether it's providing controlled drug release in pharmaceutical formulations, improving texture and stability in food products, enhancing the performance of cosmetic formulations, or optimizing the properties of construction materials, HPMC plays a vital role.HPMC offers numerous benefits due to its unique properties, making it a valuable ingredient in many products.

• Pharmaceutical Benefits:

a. Controlled Drug Release: HPMC is commonly used as a matrix former in oral solid dosage forms, such as tablets and capsules. It provides controlled drug release, ensuring a steady and sustained release of the active pharmaceutical ingredient (API) over an extended period. This feature is particularly beneficial for drugs that require a slow release pattern to maintain therapeutic efficacy.

b. Film Coating: HPMC forms a uniform and smooth film when applied to tablets or capsules, offering protection against environmental factors such as moisture, light, and air. It also improves the appearance, swallowability, and stability of the dosage form.

c. Mucoadhesive Properties: HPMC can adhere to the mucosal surfaces, enhancing the contact time and improving drug absorption. This property is useful in the development of various oral and ocular drug delivery systems.

• Food Benefits:

a. Thickening and Stabilization: HPMC acts as a thickening and stabilizing agent in food products. It imparts viscosity, texture, and creaminess to sauces, dressings, and dairy products. It prevents phase separation and maintains the homogeneity of food formulations.

b. Fat Replacement: HPMC can be used as a fat replacer in low-fat food products. It mimics the mouthfeel and texture of fats, providing a desirable sensory experience while reducing the calorie content.

c. Water Retention: HPMC has the ability to retain water, thereby preventing moisture loss and maintaining the juiciness and freshness of food products. It is particularly useful in baked goods, where it improves shelf life and texture.

• Cosmetics Benefits:

a. Thickening and Emulsifying Agent: HPMC cellulose is widely used in cosmetic formulations, such as creams, lotions, and shampoos, due to its excellent thickening and emulsifying properties. It improves the stability and consistency of cosmetic products, allowing for better spreadability and ease of application.

b. Film-Forming: When applied to the skin or hair, HPMC cellulose forms a protective film that helps to retain moisture, reducing water loss and maintaining hydration. It also enhances the longevity of cosmetic products on the skin or hair surface.

c. Suspending Agent: HPMC can suspend solid particles in cosmetic formulations, preventing their settling or sedimentation. This property is particularly useful in suspensions, scrubs, and exfoliating products.

• Construction Benefits:

a. Cement and Mortar Additive: HPMC acts as a thickener and water-retaining agent in cement-based products, such as mortars, tile adhesives, and renders. It improves workability, adhesion, and sag resistance, while reducing cracking and shrinkage.

b. Improved Open Time: Open time refers to the duration during which a construction material remains workable after application. HPMC extends the open time of adhesives, allowing for easier positioning and adjustment of tiles, wallpapers, and other materials.

c. Water Resistance: HPMC enhances the water resistance of construction materials, making them more durable and resistant to moisture-related damage. It improves the overall performance and lifespan of buildings and structures.

Overall, the hydroxypropyl methylcellulose benefits are vast and diverse. Its multifunctional properties make it an essential ingredient in a wide range of products, providing improved performance, stability, and user experience. As research and technology continue to advance, HPMC celluloseis likely to find even more applications in various industries, further demonstrating its value and versatility.

Der Herstellungs prozess von Hydroxy propyl methyl cellulose (HPMC) umfasst mehrere Schritte, um Cellulose zu modifizieren, ein natürliches Polymer, das aus pflanzlichen Quellen gewonnen wird. Das Verfahren umfasst eine chemische Behandlung und Reaktion, um Hydroxy propyl-und Methyl gruppen auf das Cellulose rückgrat einzuführen. Lassen Sie uns den Herstellungs prozess von HPMC im Detail untersuchen.

• Zellulose extraktion:

Der Prozess beginnt mit der Extraktion von Cellulose aus pflanzlichen Quellen. Übliche Quellen sind Zellstoff, Baumwolle oder andere faserige Pflanzen materialien. Die Cellulose wird typischer weise durch eine Reihe von mechanischen und chemischen Behandlungen erhalten, bei denen das Pflanzen material abgebaut und Verunreinigungen entfernt werden, um ein gereinigtes Cellulose material zu erhalten.

• Alkali-Behandlung:

Sobald die Cellulose extrahiert ist, wird sie einer Alkali behandlung unterzogen, um Hemi cellulose-und Lignin komponenten zu entfernen. Diese Behandlung beinhaltet das Eintauchen von Cellulose in eine alkalische Lösung wie Natrium hydroxid (NaOH), um die nicht cellulose haltigen Materialien abzubauen. Das Ergebnis ist gereinigte Cellulose mit einem höheren Reinheit sgrad.

• Verether ung:

Der nächste Schritt ist der Verether ungs prozess, bei dem Hydroxy propyl-und Methyl gruppen in das Cellulose rückgrat eingeführt werden. Dies wird durch eine Reihe von Reaktionen erreicht, an denen die Cellulose und geeignete Reagenzien beteiligt sind.

A. Alkali aktivierung: Die gereinigte Cellulose wird in einer Alkali lösung, typischer weise Natrium hydroxid, suspendiert, um die Cellulose zu aktivieren und reaktiver zu machen.

B. Hydroxy propylierung: Die aktivierte Cellulose wird dann mit Propylen oxid (PO) oder einer ähnlichen Verbindung behandelt. Die Hydroxy propyl gruppe aus dem PO reagiert mit den Cellulose hydroxylgruppen, was zur Bindung von Hydroxy propyl gruppen an das Cellulose rückgrat führt.

C. Methyl ierung: Nach dem Hydroxy propylierung schritt wird die Cellulose mit gebundenen Hydroxy propyl gruppen einer Methyl ierung unterzogen. Dies beinhaltet die Reaktion der hydroxy propylierten Cellulose mit Methyl chlorid oder einem ähnlichen Methyl ierungs mittel. Die Methyl gruppe aus dem Methyl ierungs mittel reagiert mit den verbleibenden Hydroxylgruppen auf der Cellulose, was zur Einführung von Methyl gruppen auf das Cellulose rückgrat führt.

• Neutral isierung und Waschen:

Nach dem Verether ungs prozess wird das Reaktions gemisch neutral isiert, um weitere Reaktionen zu stoppen und den pH-Wert einzustellen. Saure oder basische Lösungen werden hinzugefügt, um übers chüssiges Alkali oder Säure in der Mischung zu neutralisieren. Das neutral isierte Gemisch wird dann gründlich gewaschen, um alle Rest reagenzien oder Nebenprodukte zu entfernen, um ein gereinigtes HPMC-Produkt sicher zustellen.

• Trocknen und Fräsen:

Der letzte Schritt im HPMC-Herstellungs prozess umfasst das Trocknen und Mahlen des erhaltenen HPMC-Produkts. Das Produkt wird typischer weise unter Verwendung von Heißluft-oder Vakuum trocknungs methoden getrocknet, um Feuchtigkeit zu entfernen und ein trockenes Pulver zu erhalten. Das getrocknete HPMC wird dann gemahlen, um die gewünschte Partikel größe und Gleichmäßigkeit zu erreichen, was zu einem feinen Pulver führt, das für die Verpackung und Verteilung bereit ist.

Es ist erwähnens wert, dass der spezifische Herstellungs prozess von HPMC zwischen verschiedenen Herstellern und ihren proprietären Methoden leicht variieren kann. Die allgemeinen Grundsätze und Schritte des Prozesses bleiben jedoch konsistent.

Zusammenfassend lässt sich sagen, dass der Herstellungs prozess von Hydroxy propyl methyl cellulose (HPMC) die Extraktion von Cellulose aus pflanzlichen Quellen umfasst, gefolgt von Alkali behandlung, Alkali aktivierung, Hydroxy propylierung, Methyl ierung, Neutralisation, Waschen, Trocknen, und Fräsen. Dieser Prozess führt zur Herstellung von HPMC, einer vielseitigen Verbindung mit verschiedenen Anwendungen in Branchen wie Pharmazeutika, Lebensmitteln, Kosmetika und Bauwesen.